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Efficient assembly of de novo human artificial chromosomes from large genomic loci
BACKGROUND: Human Artificial Chromosomes (HACs) are potentially useful vectors for gene transfer studies and for functional annotation of the genome because of their suitability for cloning, manipulating and transferring large segments of the genome. However, development of HACs for the transfer of...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182356/ https://www.ncbi.nlm.nih.gov/pubmed/15998466 http://dx.doi.org/10.1186/1472-6750-5-21 |