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Immediate transfection of patient-derived leukemia: a novel source for generating cell-based vaccines

BACKGROUND: The production of cell-based cancer vaccines by gene vectors encoding proteins that stimulate the immune system has advanced rapidly in model systems. We sought to develop non-viral transfection methods that could transform patient tumor cells into cancer vaccines, paving the way for rap...

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Detalles Bibliográficos
Autores principales: Gershan, Jill A, Johnson, Bryon D, Weber, James, Schauer, Dennis W, Natalia, Natalia, Behnke, Stephanie, Burns, Karen, Maloney, Kelly W, Warwick, Anne B, Orentas, Rimas J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182385/
https://www.ncbi.nlm.nih.gov/pubmed/15969754
http://dx.doi.org/10.1186/1479-0556-3-4