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Chemically synthesized zinc finger molecules as nano-addressable probes for double-stranded DNAs

Our experiments describe an alternative method of dsDNA recognition using zinc finger (ZF) molecules which bind DNA specifically and with high affinity. Our aim was to develop zinc finger probes which are able to bind to dsDNA molecules at predetermined sites. In our basic approach we used pairs of...

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Detalles Bibliográficos
Autores principales: von Nickisch-Rosenegk, Markus, Ehrentreich-Forster, Eva, Strehlow, Rothin, Christmann, Alexander, Bier, Frank F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182392/
https://www.ncbi.nlm.nih.gov/pubmed/15985184
http://dx.doi.org/10.1186/1477-3155-3-5