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Information theory-based algorithm for in silico prediction of PCR products with whole genomic sequences as templates

BACKGROUND: A new algorithm for assessing similarity between primer and template has been developed based on the hypothesis that annealing of primer to template is an information transfer process. RESULTS: Primer sequence is converted to a vector of the full potential hydrogen numbers (3 for G or C,...

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Detalles Bibliográficos
Autores principales: Cao, Youfang, Wang, Lianjie, Xu, Kexue, Kou, Chunhai, Zhang, Yulei, Wei, Guifang, He, Junjian, Wang, Yunfang, Zhao, Liping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183192/
https://www.ncbi.nlm.nih.gov/pubmed/16042814
http://dx.doi.org/10.1186/1471-2105-6-190