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Response rate of fibrosarcoma cells to cytotoxic drugs on the expression level correlates to the therapeutic response rate of fibrosarcomas and is mediated by regulation of apoptotic pathways

BACKGROUND: Because of the high resistance rate of fibrosarcomas against cytotoxic agents clinical chemotherapy of these tumors is not established. A better understanding of the diverse modes of tumor cell death following cytotoxic therapies will provide a molecular basis for new chemotherapeutic st...

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Detalles Bibliográficos
Autores principales: Lehnhardt, Marcus, Klein-Hitpass, Ludger, Kuhnen, Cornelius, Homann, Heinz Herbert, Daigeler, Adrien, Steinau, Hans Ulrich, Roehrs, Sonja, Schnoor, Laura, Steinstraesser, Lars, Mueller, Oliver
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183194/
https://www.ncbi.nlm.nih.gov/pubmed/16001973
http://dx.doi.org/10.1186/1471-2407-5-74