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Response rate of fibrosarcoma cells to cytotoxic drugs on the expression level correlates to the therapeutic response rate of fibrosarcomas and is mediated by regulation of apoptotic pathways
BACKGROUND: Because of the high resistance rate of fibrosarcomas against cytotoxic agents clinical chemotherapy of these tumors is not established. A better understanding of the diverse modes of tumor cell death following cytotoxic therapies will provide a molecular basis for new chemotherapeutic st...
Autores principales: | Lehnhardt, Marcus, Klein-Hitpass, Ludger, Kuhnen, Cornelius, Homann, Heinz Herbert, Daigeler, Adrien, Steinau, Hans Ulrich, Roehrs, Sonja, Schnoor, Laura, Steinstraesser, Lars, Mueller, Oliver |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183194/ https://www.ncbi.nlm.nih.gov/pubmed/16001973 http://dx.doi.org/10.1186/1471-2407-5-74 |
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