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PI3K and PKC contribute to membrane depolarization mediated by α(2)-adrenoceptors in the canine isolated mesenteric vein

BACKGROUND: Norepinephrine (NE), a classic neurotransmitter in the sympathetic nervous system, induces vasoconstriction of canine isolated mesenteric vein that is accompanied by a sustained membrane depolarization. The mechanisms underlying the NE-elicited membrane depolarization remain undefined. I...

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Detalles Bibliográficos
Autores principales: Yamboliev, Ilia A, Mutafova-Yambolieva, Violeta N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183225/
https://www.ncbi.nlm.nih.gov/pubmed/15958164
http://dx.doi.org/10.1186/1472-6793-5-9