Ab Initio Prediction of Transcription Factor Targets Using Structural Knowledge

Current approaches for identification and detection of transcription factor binding sites rely on an extensive set of known target genes. Here we describe a novel structure-based approach applicable to transcription factors with no prior binding data. Our approach combines sequence data and structur...

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Detalles Bibliográficos
Autores principales: Kaplan, Tommy, Friedman, Nir, Margalit, Hanah
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183507/
https://www.ncbi.nlm.nih.gov/pubmed/16103898
http://dx.doi.org/10.1371/journal.pcbi.0010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183507/
https://www.ncbi.nlm.nih.gov/pubmed/16103898
http://dx.doi.org/10.1371/journal.pcbi.0010001

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