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Susceptibility to Neurodegeneration in a Glaucoma Is Modified by Bax Gene Dosage

In glaucoma, harmful intraocular pressure often contributes to retinal ganglion cell death. It is not clear, however, if intraocular pressure directly insults the retinal ganglion cell axon, the soma, or both. The pathways that mediate pressure-induced retinal ganglion cell death are poorly defined,...

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Detalles Bibliográficos
Autores principales: Libby, Richard T, Li, Yan, Savinova, Olga V, Barter, Joseph, Smith, Richard S, Nickells, Robert W, John, Simon W.M
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183523/
https://www.ncbi.nlm.nih.gov/pubmed/16103918
http://dx.doi.org/10.1371/journal.pgen.0010004