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New Genes Tied to Endocrine, Metabolic, and Dietary Regulation of Lifespan from a Caenorhabditis elegans Genomic RNAi Screen

Most of our knowledge about the regulation of aging comes from mutants originally isolated for other phenotypes. To ask whether our current view of aging has been affected by selection bias, and to deepen our understanding of known longevity pathways, we screened a genomic Caenorhabditis elegans RNA...

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Detalles Bibliográficos
Autores principales: Hansen, Malene, Hsu, Ao-Lin, Dillin, Andrew, Kenyon, Cynthia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183531/
https://www.ncbi.nlm.nih.gov/pubmed/16103914
http://dx.doi.org/10.1371/journal.pgen.0010017