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Quantitative analysis of EGR proteins binding to DNA: assessing additivity in both the binding site and the protein

BACKGROUND: Recognition codes for protein-DNA interactions typically assume that the interacting positions contribute additively to the binding energy. While this is known to not be precisely true, an additive model over the DNA positions can be a good approximation, at least for some proteins. Much...

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Detalles Bibliográficos
Autores principales: Liu, Jiajian, Stormo, Gary D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184061/
https://www.ncbi.nlm.nih.gov/pubmed/16014175
http://dx.doi.org/10.1186/1471-2105-6-176