Modulation of p53 activity by IκBα: Evidence suggesting a common phylogeny between NF-κB and p53 transcription factors

BACKGROUND: In this work we present evidence that the p53 tumor suppressor protein and NF-κB transcription factors could be related through common descent from a family of ancestral transcription factors regulating cellular proliferation and apoptosis. P53 is a homotetrameric transcription factor kn...

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Detalles Bibliográficos
Autores principales: Dreyfus, David H, Nagasawa, Masayuki, Gelfand, Erwin W, Ghoda, Lucy Y
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184076/
https://www.ncbi.nlm.nih.gov/pubmed/15969767
http://dx.doi.org/10.1186/1471-2172-6-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184076/
https://www.ncbi.nlm.nih.gov/pubmed/15969767
http://dx.doi.org/10.1186/1471-2172-6-12

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