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Is neutrophil elastase the missing link between emphysema and fibrosis? Evidence from two mouse models

BACKGROUND: The separation of emphysema from fibrosis is not as clear-cut as it was thought in early studies. These two pathologies may be present at the same time in human lungs and in mice either instilled with elastolytic enzymes or bleomycin or exposed to cigarette-smoke. According to a current...

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Detalles Bibliográficos
Autores principales: Lucattelli, Monica, Bartalesi, Barbara, Cavarra, Eleonora, Fineschi, Silvia, Lunghi, Benedetta, Martorana, Piero A, Lungarella, Giuseppe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184102/
https://www.ncbi.nlm.nih.gov/pubmed/16045796
http://dx.doi.org/10.1186/1465-9921-6-83