siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

A growing body of evidence suggests that siRNA could generate off-target effects through different mechanisms. However, the full impact of off-target gene regulation on phenotypic induction and accordingly on data interpretation in the context of large-scale siRNA library screen has not been reporte...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Xiaoyu, Ruan, Xiaoan, Anderson, Mark G., McDowell, Jeffrey A., Kroeger, Paul E., Fesik, Stephen W., Shen, Yu
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184219/
https://www.ncbi.nlm.nih.gov/pubmed/16091630
http://dx.doi.org/10.1093/nar/gki762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184219/
https://www.ncbi.nlm.nih.gov/pubmed/16091630
http://dx.doi.org/10.1093/nar/gki762

Ejemplares similares