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Alterations of tumor suppressor gene p16(INK4a )in pancreatic ductal carcinoma

BACKGROUND: Cell cycle inhibitor and tumor suppressor gene p16 / MTS-1 has been reported to be altered in a variety of human tumors. The purpose of the study was to evaluate primary pancreatic ductal adenocarcinomas for potentially inactivating p16 alterations. METHODS: We investigated the status of...

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Detalles Bibliográficos
Autores principales: Attri, Jyotika, Srinivasan, Radhika, Majumdar, Siddhartha, Radotra, Bishan Dass, Wig, Jaidev
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1185532/
https://www.ncbi.nlm.nih.gov/pubmed/15985168
http://dx.doi.org/10.1186/1471-230X-5-22