Changes in P-glycoprotein activity are mediated by the growth of a tumour cell line as multicellular spheroids

BACKGROUND: Expression of P-glycoprotein (P-gp), the multidrug resistance (MDR) 1 gene product, can lead to multidrug resistance in tumours. However, the physiological role of P-gp in tumours growing as multicellular spheroids is not well understood. Recent evidence suggests that P-gp activity may b...

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Detalles Bibliográficos
Autores principales: Valeria, Ponce de León, Raúl, Barrera-Rodríguez
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1185553/
https://www.ncbi.nlm.nih.gov/pubmed/16001980
http://dx.doi.org/10.1186/1475-2867-5-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1185553/
https://www.ncbi.nlm.nih.gov/pubmed/16001980
http://dx.doi.org/10.1186/1475-2867-5-20

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