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Determination of the relative amounts of Gag and Pol proteins in foamy virus particles

We determined the relative ratios of Gag and Pol molecules in highly purified virions of spumaretroviruses or foamy viruses (FVs) using monoclonal antibodies and bacterially expressed reference proteins. We found that the cleaved p68(Gag )moiety dominates in infectious FVs. Furthermore, approximate...

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Detalles Bibliográficos
Autores principales: Cartellieri, Marc, Rudolph, Wolfram, Herchenröder, Ottmar, Lindemann, Dirk, Rethwilm, Axel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1185564/
https://www.ncbi.nlm.nih.gov/pubmed/16004609
http://dx.doi.org/10.1186/1742-4690-2-44