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Recognition of Unknown Conserved Alternatively Spliced Exons

The split structure of most mammalian protein-coding genes allows for the potential to produce multiple different mRNA and protein isoforms from a single gene locus through the process of alternative splicing (AS). We propose a computational approach called UNCOVER based on a pair hidden Markov mode...

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Detalles Bibliográficos
Autores principales: Ohler, Uwe, Shomron, Noam, Burge, Christopher B
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1185642/
https://www.ncbi.nlm.nih.gov/pubmed/16110330
http://dx.doi.org/10.1371/journal.pcbi.0010015