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Oscillating Evolution of a Mammalian Locus with Overlapping Reading Frames: An XLαs/ALEX Relay

XLαs and ALEX are structurally unrelated mammalian proteins translated from alternative overlapping reading frames of a single transcript. Not only are they encoded by the same locus, but a specific XLαs/ALEX interaction is essential for G-protein signaling in neuroendocrine cells. A disruption of t...

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Detalles Bibliográficos
Autores principales: Nekrutenko, Anton, Wadhawan, Samir, Goetting-Minesky, Paula, Makova, Kateryna D
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1186735/
https://www.ncbi.nlm.nih.gov/pubmed/16110341
http://dx.doi.org/10.1371/journal.pgen.0010018