Cargando…
Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal
The structure of human telomere DNA is of intense interest because of its role in the biology of both cancer and aging. The sequence [5′-AGGG(TTAGGG)(3)] has been used as a model for telomere DNA in both NMR and X-ray crystallographic studies, the results of which show dramatically different structu...
| Autores principales: | , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187823/ https://www.ncbi.nlm.nih.gov/pubmed/16106044 http://dx.doi.org/10.1093/nar/gki782 |