Cargando…

Anti-Fas mAb-induced apoptosis and cytolysis of airway tissue eosinophils aggravates rather than resolves established inflammation

BACKGROUND: Fas receptor-mediated eosinophil apoptosis is currently forwarded as a mechanism resolving asthma-like inflammation. This view is based on observations in vitro and in airway lumen with unknown translatability to airway tissues in vivo. In fact, apoptotic eosinophils have not been detect...

Descripción completa

Detalles Bibliográficos
Autores principales: Uller, Lena, Rydell-Törmänen, Kristina, Persson, Carl GA, Erjefält, Jonas S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187926/
https://www.ncbi.nlm.nih.gov/pubmed/16086832
http://dx.doi.org/10.1186/1465-9921-6-90