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Overexpression of cathepsin K during silica-induced lung fibrosis and control by TGF-β

BACKGROUND: Lung fibrosis is characterized by tissue remodeling resulting from an imbalance between synthesis and degradation of extracellular organic matrices. To examine whether cathepsin(s) (Cat) are important in the development of pulmonary fibrosis, we assessed the expression of four Cat known...

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Detalles Bibliográficos
Autores principales: van den Brûle, Sybille, Misson, Pierre, Bühling, Frank, Lison, Dominique, Huaux, François
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1188077/
https://www.ncbi.nlm.nih.gov/pubmed/16045809
http://dx.doi.org/10.1186/1465-9921-6-84