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The Zebrafish Mutants dre, uki, and lep Encode Negative Regulators of the Hedgehog Signaling Pathway

Proliferation is one of the basic processes that control embryogenesis. To identify factors involved in the regulation of proliferation, we performed a zebrafish genetic screen in which we used proliferating cell nuclear antigen (PCNA) expression as a readout. Two mutants, hu418B and hu540A, show in...

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Detalles Bibliográficos
Autores principales: Koudijs, Marco J, den Broeder, Marjo J., Keijser, Astrid, Wienholds, Erno, Houwing, Saskia, van Rooijen, Ellen M. H. C., Geisler, Robert, van Eeden, Fredericus J. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1189072/
https://www.ncbi.nlm.nih.gov/pubmed/16121254
http://dx.doi.org/10.1371/journal.pgen.0010019