Medium-Chain Acyl-CoA Dehydrogenase Deficiency in Gene-Targeted Mice

Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is the most common inherited disorder of mitochondrial fatty acid β-oxidation in humans. To better understand the pathogenesis of this disease, we developed a mouse model for MCAD deficiency (MCAD(−/−)) by gene targeting in embryonic stem (ES) ce...

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Detalles Bibliográficos
Autores principales: Tolwani, Ravi J, Hamm, Doug A, Tian, Liqun, Sharer, J. Daniel, Vockley, Jerry, Rinaldo, Piero, Matern, Dietrich, Schoeb, Trenton R, Wood, Philip A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1189074/
https://www.ncbi.nlm.nih.gov/pubmed/16121256
http://dx.doi.org/10.1371/journal.pgen.0010023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1189074/
https://www.ncbi.nlm.nih.gov/pubmed/16121256
http://dx.doi.org/10.1371/journal.pgen.0010023

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