In normal rat, intraventricularly administered insulin-like growth factor-1 is rapidly cleared from CSF with limited distribution into brain

BACKGROUND: Putatively active drugs are often intraventricularly administered to gain direct access to brain and circumvent the blood-brain barrier. A few studies on the normal central nervous system (CNS) have shown, however, that the distribution of materials after intraventricular injections is m...

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Detalles Bibliográficos
Autores principales: Nagaraja, Tavarekere N, Patel, Padma, Gorski, Martin, Gorevic, Peter D, Patlak, Clifford S, Fenstermacher, Joseph D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1190198/
https://www.ncbi.nlm.nih.gov/pubmed/16045806
http://dx.doi.org/10.1186/1743-8454-2-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1190198/
https://www.ncbi.nlm.nih.gov/pubmed/16045806
http://dx.doi.org/10.1186/1743-8454-2-5

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