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Full cyclic coordinate descent: solving the protein loop closure problem in Cα space
BACKGROUND: Various forms of the so-called loop closure problem are crucial to protein structure prediction methods. Given an N- and a C-terminal end, the problem consists of finding a suitable segment of a certain length that bridges the ends seamlessly. In homology modelling, the problem arises in...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1192790/ https://www.ncbi.nlm.nih.gov/pubmed/15985178 http://dx.doi.org/10.1186/1471-2105-6-159 |