Cargando…

Full cyclic coordinate descent: solving the protein loop closure problem in Cα space

BACKGROUND: Various forms of the so-called loop closure problem are crucial to protein structure prediction methods. Given an N- and a C-terminal end, the problem consists of finding a suitable segment of a certain length that bridges the ends seamlessly. In homology modelling, the problem arises in...

Descripción completa

Detalles Bibliográficos
Autores principales: Boomsma, Wouter, Hamelryck, Thomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1192790/
https://www.ncbi.nlm.nih.gov/pubmed/15985178
http://dx.doi.org/10.1186/1471-2105-6-159