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Involvement of KSRP in the post-transcriptional regulation of human iNOS expression–complex interplay of KSRP with TTP and HuR

We purified the KH-type splicing regulatory protein (KSRP) as a protein interacting with the 3′-untranslated region (3′-UTR) of the human inducible nitric oxide (iNOS) mRNA. Immunodepletion of KSRP enhanced iNOS 3′-UTR RNA stability in in vitro-degradation assays. In DLD-1 cells overexpressing KSRP...

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Detalles Bibliográficos
Autores principales: Linker, Katrin, Pautz, Andrea, Fechir, Marcel, Hubrich, Thomas, Greeve, Jobst, Kleinert, Hartmut
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1192834/
https://www.ncbi.nlm.nih.gov/pubmed/16126846
http://dx.doi.org/10.1093/nar/gki797