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Cisplatin Nephrotoxicity and Protection by Milk Thistle Extract in Rats
The protective effect of methanolic extract of milk thistle seeds and silymarin against cisplatin-induced renal toxicity in male rats after a single intraperitoneal injection of 3 mg kg(−1) cisplatin were studied. Over 5 days, cisplatin-treated rats showed tubular necrosis and elevation in blood ure...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1193544/ https://www.ncbi.nlm.nih.gov/pubmed/16136217 http://dx.doi.org/10.1093/ecam/neh103 |