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NEIL1 excises 3′ end proximal oxidative DNA lesions resistant to cleavage by NTH1 and OGG1

Base excision repair is the major pathway for the repair of oxidative DNA damage in human cells that is initiated by a damage-specific DNA glycosylase. In human cells, the major DNA glycosylases for the excision of oxidative base damage are OGG1 and NTH1 that excise 8-oxoguanine and oxidative pyrimi...

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Detalles Bibliográficos
Autores principales: Parsons, Jason L., Zharkov, Dmitry O., Dianov, Grigory L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1196207/
https://www.ncbi.nlm.nih.gov/pubmed/16129732
http://dx.doi.org/10.1093/nar/gki816