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Herpes simplex virus interferes with amyloid precursor protein processing

BACKGROUND: The early events underlying Alzheimer's disease (AD) remain uncertain, although environmental factors may be involved. Work in this laboratory has shown that the combination of herpes simplex virus type 1 (HSV1) in brain and carriage of the APOE-ε4 allele of the APOE gene strongly i...

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Detalles Bibliográficos
Autores principales: Shipley, Suzanne J, Parkin, Edward T, Itzhaki, Ruth F, Dobson, Curtis B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1198230/
https://www.ncbi.nlm.nih.gov/pubmed/16109164
http://dx.doi.org/10.1186/1471-2180-5-48