NPC1L1 haplotype is associated with inter-individual variation in plasma low-density lipoprotein response to ezetimibe

BACKGROUND: NPC1L1 encodes a putative intestinal sterol transporter which is the likely target for ezetimibe, a new type of lipid-lowering medication. We previously reported rare non-synonymous mutations in NPC1L1 in an individual who had no plasma lipoprotein response to ezetimibe. We next hypothes...

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Detalles Bibliográficos
Autores principales: Hegele, Robert A, Guy, Justin, Ban, Matthew R, Wang, Jian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1198250/
https://www.ncbi.nlm.nih.gov/pubmed/16098225
http://dx.doi.org/10.1186/1476-511X-4-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1198250/
https://www.ncbi.nlm.nih.gov/pubmed/16098225
http://dx.doi.org/10.1186/1476-511X-4-16

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