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Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease

BACKGROUND: Morbidity in COPD results from a combination of factors including hypoxia-induced pulmonary hypertension, in part due to pulmonary vascular remodelling. Animal studies suggest a role of angiotensin II and acute studies in man concur. Whether chronic angiotensin-II blockade is beneficial...

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Detalles Bibliográficos
Autores principales: Morrell, Nicholas W, Higham, Matthew A, Phillips, Peter G, Shakur, B Haleema, Robinson, Paul J, Beddoes, Ray J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1198258/
https://www.ncbi.nlm.nih.gov/pubmed/16060962
http://dx.doi.org/10.1186/1465-9921-6-88