The Gumbel pre-factor k for gapped local alignment can be estimated from simulations of global alignment

The optimal gapped local alignment score of two random sequences follows a Gumbel distribution. The Gumbel distribution has two parameters, the scale parameter λ and the pre-factor k. Presently, the basic local alignment search tool (BLAST) programs (BLASTP (BLAST for proteins), PSI-BLAST, etc.) use...

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Detalles Bibliográficos
Autores principales: Sheetlin, Sergey, Park, Yonil, Spouge, John L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199557/
https://www.ncbi.nlm.nih.gov/pubmed/16147981
http://dx.doi.org/10.1093/nar/gki800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199557/
https://www.ncbi.nlm.nih.gov/pubmed/16147981
http://dx.doi.org/10.1093/nar/gki800

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