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A thermodynamic approach to designing structure-free combinatorial DNA word sets

An algorithm is presented for the generation of sets of non-interacting DNA sequences, employing existing thermodynamic models for the prediction of duplex stabilities and secondary structures. A DNA ‘word’ structure is employed in which individual DNA ‘words’ of a given length (e.g. 12mer and 16mer...

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Detalles Bibliográficos
Autores principales: Shortreed, Michael R., Chang, Seo Bong, Hong, DongGee, Phillips, Maggie, Campion, Bridget, Tulpan, Dan C., Andronescu, Mirela, Condon, Anne, Hoos, Holger H., Smith, Lloyd M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199559/
https://www.ncbi.nlm.nih.gov/pubmed/16284197
http://dx.doi.org/10.1093/nar/gki812