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A thermodynamic approach to designing structure-free combinatorial DNA word sets
An algorithm is presented for the generation of sets of non-interacting DNA sequences, employing existing thermodynamic models for the prediction of duplex stabilities and secondary structures. A DNA ‘word’ structure is employed in which individual DNA ‘words’ of a given length (e.g. 12mer and 16mer...
Autores principales: | Shortreed, Michael R., Chang, Seo Bong, Hong, DongGee, Phillips, Maggie, Campion, Bridget, Tulpan, Dan C., Andronescu, Mirela, Condon, Anne, Hoos, Holger H., Smith, Lloyd M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199559/ https://www.ncbi.nlm.nih.gov/pubmed/16284197 http://dx.doi.org/10.1093/nar/gki812 |
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