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Thermodynamically based DNA strand design

We describe a new algorithm for design of strand sets, for use in DNA computations or universal microarrays. Our algorithm can design sets that satisfy any of several thermodynamic and combinatorial constraints, which aim to maximize desired hybridizations between strands and their complements, whil...

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Detalles Bibliográficos
Autores principales: Tulpan, Dan, Andronescu, Mirela, Chang, Seo Bong, Shortreed, Michael R., Condon, Anne, Hoos, Holger H., Smith, Lloyd M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199561/
https://www.ncbi.nlm.nih.gov/pubmed/16145053
http://dx.doi.org/10.1093/nar/gki773