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Thermodynamically based DNA strand design
We describe a new algorithm for design of strand sets, for use in DNA computations or universal microarrays. Our algorithm can design sets that satisfy any of several thermodynamic and combinatorial constraints, which aim to maximize desired hybridizations between strands and their complements, whil...
Autores principales: | Tulpan, Dan, Andronescu, Mirela, Chang, Seo Bong, Shortreed, Michael R., Condon, Anne, Hoos, Holger H., Smith, Lloyd M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199561/ https://www.ncbi.nlm.nih.gov/pubmed/16145053 http://dx.doi.org/10.1093/nar/gki773 |
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