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No significant role for beta tubulin mutations and mismatch repair defects in ovarian cancer resistance to paclitaxel/cisplatin

BACKGROUND: The mechanisms of chemoresistance in ovarian cancer patients remain largely to be elucidated. Paclitaxel/cisplatin combination is the standard chemotherapeutic treatment for this disease, although some patients do not respond to therapy. Our goals were to investigate whether TUBB mutatio...

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Detalles Bibliográficos
Autores principales: Mesquita, Bárbara, Veiga, Isabel, Pereira, Deolinda, Tavares, Ana, Pinto, Isabel M, Pinto, Carla, Teixeira, Manuel R, Castedo, Sérgio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199587/
https://www.ncbi.nlm.nih.gov/pubmed/16095531
http://dx.doi.org/10.1186/1471-2407-5-101