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Absence of pathogenic mitochondrial DNA mutations in mouse brain tumors
BACKGROUND: Somatic mutations in the mitochondrial genome occur in numerous tumor types including brain tumors. These mutations are generally found in the hypervariable regions I and II of the displacement loop and unlikely alter mitochondrial function. Two hypervariable regions of mononucleotide re...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199588/ https://www.ncbi.nlm.nih.gov/pubmed/16105171 http://dx.doi.org/10.1186/1471-2407-5-102 |