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A role for MCP-1/CCR2 in interstitial lung disease in children

BACKGROUND: Interstitial lung diseases (ILD) are chronic inflammatory disorders leading to pulmonary fibrosis. Monocyte chemotactic protein 1 (MCP-1) promotes collagen synthesis and deletion of the MCP-1 receptor CCR2 protects from pulmonary fibrosis in ILD mouse models. We hypothesized that pulmona...

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Detalles Bibliográficos
Autores principales: Hartl, Dominik, Griese, Matthias, Nicolai, Thomas, Zissel, Gernot, Prell, Christine, Reinhardt, Dietrich, Schendel, Dolores J, Krauss-Etschmann, Susanne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199626/
https://www.ncbi.nlm.nih.gov/pubmed/16095529
http://dx.doi.org/10.1186/1465-9921-6-93