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Repeated high doses of avermectins cause prolonged sterilisation, but do not kill, Onchocerca ochengi adult worms in African cattle

BACKGROUND: Ivermectin (Mectizan™, Merck and CO. Inc.) is being widely used in the control of human onchocerciasis (Onchoverca volvulus) because of its potent effect on microfilariae. Human studies have suggested that, at the standard dose of 150 μg/kg an annual treatment schedule of ivermectin reve...

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Detalles Bibliográficos
Autores principales: deC Bronsvoort, Barend M, Renz, Alfons, Tchakouté, Virginia, Tanya, Vincent N, Ekale, David, Trees, Alexander J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200428/
https://www.ncbi.nlm.nih.gov/pubmed/16086838
http://dx.doi.org/10.1186/1475-2883-4-8