Extended base pair complementarity between U1 snRNA and the 5′ splice site does not inhibit splicing in higher eukaryotes, but rather increases 5′ splice site recognition

Spliceosome formation is initiated by the recognition of the 5′ splice site through formation of an RNA duplex between the 5′ splice site and U1 snRNA. We have previously shown that RNA duplex formation between U1 snRNA and the 5′ splice site can protect pre-mRNAs from degradation prior to splicing....

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Detalles Bibliográficos
Autores principales: Freund, Marcel, Hicks, Martin J., Konermann, Carolin, Otte, Marianne, Hertel, Klemens J., Schaal, Heiner
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201333/
https://www.ncbi.nlm.nih.gov/pubmed/16155183
http://dx.doi.org/10.1093/nar/gki824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201333/
https://www.ncbi.nlm.nih.gov/pubmed/16155183
http://dx.doi.org/10.1093/nar/gki824

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