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RNase P: role of distinct protein cofactors in tRNA substrate recognition and RNA-based catalysis
The Escherichia coli ribonuclease P (RNase P) has a protein component, termed C5, which acts as a cofactor for the catalytic M1 RNA subunit that processes the 5′ leader sequence of precursor tRNA. Rpp29, a conserved protein subunit of human RNase P, can substitute for C5 protein in reconstitution as...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201335/ https://www.ncbi.nlm.nih.gov/pubmed/16155184 http://dx.doi.org/10.1093/nar/gki828 |