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Human vault-associated non-coding RNAs bind to mitoxantrone, a chemotherapeutic compound
Human vaults are the largest cytoplasmic ribonucleoprotein and are overexpressed in cancer cells. Vaults reportedly function in the extrusion of xenobiotics from the nuclei of resistant cells, but the interactions of xenobiotics with the vault-associated proteins or non-coding RNAs have never been d...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201340/ https://www.ncbi.nlm.nih.gov/pubmed/16150923 http://dx.doi.org/10.1093/nar/gki809 |