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Human vault-associated non-coding RNAs bind to mitoxantrone, a chemotherapeutic compound

Human vaults are the largest cytoplasmic ribonucleoprotein and are overexpressed in cancer cells. Vaults reportedly function in the extrusion of xenobiotics from the nuclei of resistant cells, but the interactions of xenobiotics with the vault-associated proteins or non-coding RNAs have never been d...

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Detalles Bibliográficos
Autores principales: Gopinath, Subash C. B., Matsugami, Akimasa, Katahira, Masato, Kumar, Penmetcha K. R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1201340/
https://www.ncbi.nlm.nih.gov/pubmed/16150923
http://dx.doi.org/10.1093/nar/gki809