In B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosis

BACKGROUND: A common sequence polymorphism at codon 72 of the p53 gene encoding either arginine or proline was recently shown to be functionally relevant for apoptosis induction in vitro. In B-type chronic lymphocytic leukemia (B-CLL), p53 gene mutations occur in a subset of patients and are associa...

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Detalles Bibliográficos
Autores principales: Sturm, Isrid, Bosanquet, Andrew G, Hummel, Michael, Dörken, Bernd, Daniel, Peter T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208864/
https://www.ncbi.nlm.nih.gov/pubmed/16109171
http://dx.doi.org/10.1186/1471-2407-5-105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208864/
https://www.ncbi.nlm.nih.gov/pubmed/16109171
http://dx.doi.org/10.1186/1471-2407-5-105

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