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Pharmacological challenge with a serotonin 1D agonist in alcohol dependence

BACKGROUND: Both animal and clinical studies have implicated serotonergic dysfunction in the pathogenesis of alcohol abuse and dependence. However the exact mechanisms involved remain unknown. Theoretically, low serotonin promotes alcohol seeking behavior. Sumatriptan is a serotonin1D agonist. It is...

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Detalles Bibliográficos
Autores principales: Vythilingum, Bavanisha, Hugo, Charmaine J, Maritz, J Stefan, Pienaar, Willie, Stein, Dan J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208916/
https://www.ncbi.nlm.nih.gov/pubmed/16120224
http://dx.doi.org/10.1186/1471-244X-5-31