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A two-dimensional mathematical model of non-linear dual-sorption of percutaneous drug absorption
BACKGROUND: Certain drugs, for example scopolamine and timolol, show non-linear kinetic behavior during permeation process. This non-linear kinetic behavior is due to two mechanisms; the first mechanism being a simple dissolution producing mobile and freely diffusible molecules and the second being...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208919/ https://www.ncbi.nlm.nih.gov/pubmed/15992411 http://dx.doi.org/10.1186/1475-925X-4-40 |