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A two-dimensional mathematical model of non-linear dual-sorption of percutaneous drug absorption

BACKGROUND: Certain drugs, for example scopolamine and timolol, show non-linear kinetic behavior during permeation process. This non-linear kinetic behavior is due to two mechanisms; the first mechanism being a simple dissolution producing mobile and freely diffusible molecules and the second being...

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Detalles Bibliográficos
Autor principal: George, K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208919/
https://www.ncbi.nlm.nih.gov/pubmed/15992411
http://dx.doi.org/10.1186/1475-925X-4-40