Sulindac metabolites inhibit epidermal growth factor receptor activation and expression

BACKGROUND: Regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a decreased mortality from colorectal cancer (CRC). NSAIDs induce apoptotic cell death in colon cancer cells in vitro and inhibit growth of neoplastic colonic mucosa in vivo however, the biochemical mechanism...

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Detalles Bibliográficos
Autores principales: Pangburn, Heather A, Kraus, Hanna, Ahnen, Dennis J, Rice, Pamela L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208922/
https://www.ncbi.nlm.nih.gov/pubmed/16138927
http://dx.doi.org/10.1186/1477-3163-4-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208922/
https://www.ncbi.nlm.nih.gov/pubmed/16138927
http://dx.doi.org/10.1186/1477-3163-4-16

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