Cargando…

Sulindac metabolites inhibit epidermal growth factor receptor activation and expression

BACKGROUND: Regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a decreased mortality from colorectal cancer (CRC). NSAIDs induce apoptotic cell death in colon cancer cells in vitro and inhibit growth of neoplastic colonic mucosa in vivo however, the biochemical mechanism...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pangburn, Heather A, Kraus, Hanna, Ahnen, Dennis J, Rice, Pamela L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208922/ https://www.ncbi.nlm.nih.gov/pubmed/16138927 http://dx.doi.org/10.1186/1477-3163-4-16

Ejemplares similares

Sulindac sulfide inhibits colon cancer cell growth and downregulates specificity protein transcription factors
por: Li, Xi, et al.
Publicado: (2015)

Combination oral antiangiogenic therapy with thalidomide and sulindac inhibits tumour growth in rabbits
por: Verheul, H M W, et al.
Publicado: (1999)

Sulindac Derivatives That Activate the Peroxisome Proliferator-activated Receptor γ but Lack Cyclooxygenase Inhibition
por: Felts, Andrew S., et al.
Publicado: (2008)

Chemoprevention of Colon Cancer by DFMO, Sulindac, and NO-Sulindac Administered Individually or in Combinations in F344 Rats
por: Madka, Venkateshwar, et al.
Publicado: (2023)

Phospho-sulindac inhibits pancreatic cancer growth: NFATc1 as a drug resistance candidate
por: MURRAY, ONIKA T., et al.
Publicado: (2013)

Sulindac for stroke treatment: neuroprotective mechanism and therapy
por: Modi, Jigar Pravinchandra, et al.
Publicado: (2014)

Amine Containing Analogs of Sulindac for Cancer Prevention
por: Mathew, Bini, et al.
Publicado: (2018)

Oxazole and thiazole analogs of sulindac for cancer prevention
por: Mathew, Bini, et al.
Publicado: (2018)

Novel Non-Cyclooxygenase Inhibitory Derivative of Sulindac Inhibits Breast Cancer Cell Growth In Vitro and Reduces Mammary Tumorigenesis in Rats
por: Tinsley, Heather N., et al.
Publicado: (2023)

Inhibiting Epidermal Growth Factor Receptor at a Distance
por: Sinclair, Julie K.-L., et al.
Publicado: (2014)

Protein Expression Signatures for Inhibition of Epidermal Growth Factor Receptor-mediated Signaling
por: Myers, Matthew V., et al.
Publicado: (2012)

Selenium and sulindac are synergistic to inhibit intestinal tumorigenesis in Apc/p21 mice
por: Bi, Xiuli, et al.
Publicado: (2013)

Expression and localization of epidermal growth factor, transforming growth factor-α and epidermal growth factor receptor in the canine testis
por: TAMADA, Hiromichi, et al.
Publicado: (2015)

Sulindac plus a phospholipid is effective for polyp reduction and safer than sulindac alone in a mouse model of colorectal cancer development
por: Davis, Jennifer S., et al.
Publicado: (2020)

Epidermal Growth Factor Receptor Expression in the Corneal Epithelium
por: Peterson, Joanne L., et al.
Publicado: (2021)

Expression of transforming growth factor alpha, epidermal growth factor receptor and epidermal growth factor in precursor lesions to gastric carcinoma.
por: Filipe, M. I., et al.
Publicado: (1995)

Dermatologic Toxicities in Epidermal Growth Factor Receptor and Multikinase Inhibitors
por: Eaby-Sandy, Beth, et al.
Publicado: (2012)

Ip-10 Inhibits Epidermal Growth Factor–Induced Motility by Decreasing Epidermal Growth Factor Receptor–Mediated Calpain Activity
por: Shiraha, Hidenori, et al.
Publicado: (1999)

Colocalization of somatostatin receptors and epidermal growth factor receptors in breast cancer cells
por: Watt, Heather L, et al.
Publicado: (2006)

Epidermal growth factor receptor expression in urinary bladder cancer
por: Naik, Dayalu S. L., et al.
Publicado: (2011)

Expression of p53 & epidermal growth factor receptor in glioblastoma
por: Karnam, Sameera, et al.
Publicado: (2017)

Sulindac Enhances the Killing of Cancer Cells Exposed to Oxidative Stress
por: Marchetti, Maria, et al.
Publicado: (2009)

Sulindac Prevents Esophageal Adenocarcinomas Induced by Gastroduodenal Reflux in Rats
por: Kim, Sung Wook, et al.
Publicado: (2007)

A Desmoid Tumor Responding to Systemic Therapy With Tamoxifen and Sulindac
por: Choudhury, Hasan, et al.
Publicado: (2023)

Two independent mechanisms for escaping epidermal growth factor- mediated growth inhibition in epidermal growth factor receptor- hyperproducing human tumor cells
Publicado: (1988)

Modification of the Release of Poorly Soluble Sulindac with the APTES-Modified SBA-15 Mesoporous Silica
por: Dadej, Adrianna, et al.
Publicado: (2021)

Targeting the epidermal growth factor receptor
por: El-Rayes, B F, et al.
Publicado: (2004)

Epidermal growth factor receptor in glioblastoma
por: Xu, Hongsheng, et al.
Publicado: (2017)

Interleukin-4 receptor and epidermal growth factor receptor expression in colorectal cancer.
por: Kaklamanis, L., et al.
Publicado: (1992)

The expression of epidermal growth factor receptor 1 and human epidermal growth factor receptor 2 based on tumor location affect survival in gastric cancer
por: Li, Guo-Cai, et al.
Publicado: (2020)

Lycopene Inhibits Activation of Epidermal Growth Factor Receptor and Expression of Cyclooxygenase-2 in Gastric Cancer Cells
por: Han, Hwana, et al.
Publicado: (2019)

Sulindac inhibits tumor cell invasion by suppressing NF-κB mediated transcription of microRNAs
por: Li, Xiaobo, et al.
Publicado: (2012)

Sulindac, a non-steroidal anti-inflammatory drug, mediates breast cancer inhibition as an immune modulator
por: Yin, Tao, et al.
Publicado: (2016)

Identification of the Effects of Aspirin and Sulindac Sulfide on the Inhibition of HMGA2-Mediated Oncogenic Capacities in Colorectal Cancer
por: Ekanem, Titus Ime, et al.
Publicado: (2020)

Cyclin G2, a novel target of sulindac to inhibit cell cycle progression in colorectal cancer
por: Zhao, Hongyou, et al.
Publicado: (2020)

MicroRNA-370 inhibits the growth and metastasis of lung cancer by down-regulating epidermal growth factor receptor expression
por: Liu, Xin, et al.
Publicado: (2017)

Assessment of Epidermal Growth Factor Receptor (EGFR) expression in human meningioma
por: Wernicke, A Gabriella, et al.
Publicado: (2010)

Epidermal growth factor receptor expression in canine transitional cell carcinoma
por: HANAZONO, Kiwamu, et al.
Publicado: (2014)

Prognostic significance of epidermal growth factor receptor expression in glioma patients
por: Li, Junhong, et al.
Publicado: (2018)

The expression and prognostic value of the epidermal growth factor receptor family in glioma
por: Xu, Bin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b4g9le8p2ejbuoh3diqq0bd9l5