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Heparan sulfate proteoglycan induces the production of NO and TNF-α by murine microglia

BACKGROUND: A common feature of Alzheimer's disease (AD) pathology is the abundance of activated microglia in neuritic plaques containing amyloid-beta protein (Aβ) and associated molecules including heparan sulfate proteoglycan (HSPG). Besides the role as pathological chaperone favouring amyloi...

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Detalles Bibliográficos
Autores principales: Bussini, Simona, Meda, Lucia, Scarpini, Elio, Clementi, Emilio, Conti, Giancarlo, Tiriticco, Marco, Bresolin, Nereo, Baron, Pierluigi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208935/
https://www.ncbi.nlm.nih.gov/pubmed/16022734
http://dx.doi.org/10.1186/1742-4933-2-11